Research interests: HIV cohort and infectious disease epidemiology; operations research on service responses for priority health conditions; data harmonisation and linkage; and context-appropriate health information systems development.
David is a public health specialist with many years operational experience in primary care and infectious disease service delivery. He holds an honorary faculty position at UCL. Research interests: understanding how the malaria parasite deals with the large influx of haem associated with ingestion and degradation of haemoglobin in its digestive vacuole and the effects of antimalarials such as chloroquine, which inhibit this process.
Speciation and behaviour of free Fe III haem in aqueous solution. Interaction of Fe III haem with antimalarials and effects on haem in cultured parasites. His main research interests are in the therapeutic aspects of HIV-associated tuberculosis and drug-resistant tuberculosis, antiretroviral therapy in resource-limited settings, and the pharmacokinetics of antiretroviral and anti-tuberculosis drugs.
She participates in research projects across Africa, as well as in Asia and South America where a key interest is the support and mentoring of investigator-initiated pharmacology research projects. Computational scientist with expertise in the development of Parallel and Hybrid model computer codes for application to chemical, life and biomedical sciences.
Research is balanced between development of life science software and its application to biomedical projects where more recently the biomedical application has been cancer. Scientific interests are focused on the roles that carbohydrates play in biological processes. A demonstration of the application of computational expertise is his use of molecular modelling simulations to develop therapeutics for cancer as well as his use of data analytics and informatics methods to develop diagnostics and prognostics for cancer.
Research focuses on the molecular genetic changes in oesophageal cancer using a whole genome sequencing approach to identify mutation signatures, epigenetic changes, gene mutation, deletions and insertions with specific relevance to early diagnosis and targeted therapeutic interventions in cancer. Is one of the very rare cardiologists in South Africa who is clinically active and trained in fundamental molecular laboratory methods, combining laboratory and epidemiological skills.
Widely published in both local and international journals and books of various topics related to cardiovascular medicine. ISBN Pathfinder Player Companion. Blood of the Ancients. Plane-Hopper's Handbook. Artwork from Heroes from the Fringe. Fringe Benefits! Delve into the many non- human societies found outside of the Inner Sea region!
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